Over 480 Million People Estimated to Have COPD, World’s Third Deadliest Disease, ResMed Study Reports

  • New prevalence figure 22–126% higher than previous estimates
  • Prevalence expected to reach 592 million by 2050
  • Researchers urge global action on smoking cessation and air pollution reduction

BARCELONA, Spain, Sept. 04, 2022 (GLOBE NEWSWIRE) — Over 480 million people worldwide likely suffer from chronic obstructive pulmonary disease, or COPD, according to a late-breaking abstract led by ResMed (NYSE: RMD, ASX: RMD) presented at the European Respiratory Society Congress today.1

This figure is 22–126% higher than today’s most cited estimates, which range from 212–392 million reported over the past decade.2,3,4

COPD is a chronic, progressive disease that restricts a person’s ability to breathe. Early-stage sufferers may use inhaled medications to reduce symptoms. Advanced stages may require supplemental oxygen or mechanical ventilation in the home or hospital.

COPD-related healthcare utilization and lost productivity costs European Union countries an estimated €48.4 billion per year.5 In the United States, COPD-related hospitalizations alone cost over $3 billion a year.6

ResMed’s global analysis combined known cases of COPD plus likely cases based on known risk factors, such as smoking, and other indoor and outdoor air pollution.

Researchers expect that number to reach an estimated 592 million by 2050 if current risk factor trends continue.

“This number should be a warning,” said study co-author and ResMed Chief Medical Officer Carlos M. Nunez, M.D. “It should urge doctors to be more vigilant in screening and testing, since early treatment can enhance quality of life and longevity; urge people and their loved ones to learn and spot symptoms early; urge payers to help everyone take these proactive steps; and frankly inspire stronger, more immediate action to lower risk factors for COPD like smoking and air pollution.

“In less than a generation, we’re headed north of 600 million cases globally,” Nunez continued. “But we can curb that number and help save millions of lives with education and meaningful action.”

Am I at risk for COPD?

Leading causes of COPD are:7

  • Smoking
  • Long-term exposure to air pollutants, including dust, fumes, or chemicals
  • A rare heredity gene defect called alpha-1 antitrypsin deficiency, which your doctor can test you for

COPD symptoms

Ask your doctor if you or a loved one is experiencing:8

  • Increased shortness of breath
  • Frequent coughing or wheezing, with or without mucus
  • Daytime fatigue
  • Chest tightness

ResMed recently led a global research effort to update the world’s estimated prevalence of obstructive sleep apnea (OSA): 936 million, nearly tenfold higher than the previous figure. Lancet Respiratory Medicine published the findings in 2019.9

About ResMed
At ResMed (NYSE: RMD, ASX: RMD) we pioneer innovative solutions that treat and keep people out of the hospital, empowering them to live healthier, higher-quality lives. Our digital health technologies and cloud-connected medical devices transform care for people with sleep apnea, COPD, and other chronic diseases. Our comprehensive out-of-hospital software platforms support the professionals and caregivers who help people stay healthy in the home or care setting of their choice. By enabling better care, we improve quality of life, reduce the impact of chronic disease, and lower costs for consumers and healthcare systems in more than 140 countries. To learn more, visit ResMed.com and follow @ResMed.

References
1 Boers E et al. ERJ Suppl (ERS Congress late breaking abstract) 2022
2 GBD 2019 Murray C J L et al. (2020)
3 Adeloye D et al. J Glob Health 2015
4 Adeloye D et al. Lancet Respir Med 2022
5 « The economic burden of lung disease ». Eur Lung (Accessed 18 August 2022)
6 Perera PN et al. COPD 2012
7 COPD Foundation. https://www.copdfoundation.org/What-is-COPD/Understanding-COPD/What-Causes-COPD.aspx (Accessed 30 August 2022)
8 COPD Foundation https://www.copdfoundation.org/What-is-COPD/Understanding-COPD/What-is-COPD.aspx (Accessed 30 August 2022)
9 Benjafield AV et al. Lancet Respir Med 2019

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The Oligonucleotide Therapeutics Society’s Highly Anticipated Annual Meeting Returns in Person This Year

Featured Image for Oligonucleotide Therapeutics Society

Featured Image for Oligonucleotide Therapeutics Society

SAN DIEGO, Sept. 04, 2022 (GLOBE NEWSWIRE) — OTS is pleased to announce that, after two years of meeting virtually, the 18th Annual Oligo Meeting will include a robust in-person program live from Hilton Phoenix Resort at the Peak in Phoenix, Arizona, where delegates from many different countries can engage in lively discussions and enjoy interacting face-to-face once again. This year’s meeting, which will be held Oct. 2 – 5, is a hybrid event and will also include a virtual component allowing delegates who are unable to attend in person to enjoy the Annual Meeting from the comfort of their home or office.

The Oligonucleotide Therapeutics Society (OTS) is an open, nonprofit forum to foster academic and industry-based research and development of oligonucleotide therapeutics. The Founders’ vision was to bring together the expertise from different angles of oligonucleotide research to create synergies and to bring the field of oligonucleotides to its full therapeutic potential.

The OTS Annual Meeting is a forum for the realization of the Society’s mission and goals. At the annual meeting, anyone who is interested or involved in oligonucleotide therapeutics may attend and benefit from the incredible opportunity to learn from and engage with experts, post-docs, and students for a cross-disciplinary exchange, fostering the development of ground-breaking new ideas.

Due to the efforts and persistence of those in the field, multiple oligonucleotide therapeutic treatments have received approval from regulatory agencies around the world, two mRNA Covid-19 vaccines were created due to decades of prior development in the field, and over 100 oligonucleotide therapeutic treatments are in development for common conditions, including cancer and Alzheimer’s disease, as well as rare diseases. Incredibly, oligonucleotide therapeutics are being used to create individualized treatments for people with ultra-rare, fatal diseases.

Attendees of this year’s Oligo Meeting will hear from leading experts, students, and postdocs in the field from around the world. An array of intriguing topics will be covered, from chemistry, AI/machine learning, and genome and RNA editing to current preclinical and clinical research.

The Clinical Session is always engaging and inspiring, and this year’s session promises to continue the trend with topics such as Clinical Advances in CRISPR Cas9 Therapeutics, SLN360 and Controlling Lp(a), and Lessons Learned from ALS Clinical Trials. Speakers include notable authorities in the field at key roles in Biogen, Ionis Pharmaceuticals, Alnylam Pharmaceuticals, Intellia Therapeutics, Silence Therapeutics, and n-Lorem Foundation.

A special session is dedicated to celebrating the 20th anniversary of the Oligonucleotide Therapeutics Society, and attendees will have the privilege of hearing from founders of the OTS as well as past Board of Directors members who were there during the early days of the society, including Masad J. Damha, PhD, Gunther Hartmann, MD, PhD, Anastasia Khvorova, PhD, Art Krieg, MD, Mano Manoharan, PhD, Brett Monia, PhD, John Rossi, PhD, Georg Sczakiel, PhD, Hermona Soreq, PhD, and Cy Stein, MD, PhD.

OTS also has the privilege of presenting two OTS Lifetime Achievement Awards this year to individuals who have been influential in the field. Ryszard Kole, PhD, Professor Emeritus at the University of North Carolina, will be honored with the OTS Lifetime Achievement Award 2020 and C. Frank Bennett, PhD, the Senior Vice President of Research at Ionis Pharmaceuticals, will be honored with the OTS Lifetime Achievement Award 2021.

The Annual Meeting is open to anyone interested or involved in oligonucleotide therapeutics. Those wishing to attend in person or virtually can register at 2022oligomeeting.com.

Media Contact:

Geri Beaty
Phone: (619) 795-9458
Email: info@oligotherapeutics.org

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